Our drug candidate Alpha1H kills tumor cells quickly, both in the laboratory and in animal models and in treated patients, where the response can be measured already within a few hours. The mechanism of action has been studied in detail and the results have been published in reputed international journals.
Alpha1H attacks the cell membrane from the outside, enters the tumor cells and quickly migrates into the cell nucleus, where vital functions are inhibited in cancer cells. Along the way, Alpha1H encounters several different parts of the cell machinery and activates apoptosis; an important form of cell death that is not toxic to surrounding tissues. The molecular effects can also be read in animal models and in treated patients, with methods such as RNA sequencing and visualization of the tissues with high-resolution technology after staining for specific markers.
